Home — CAMS Oxford Institute

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Researchers from Oxford University & New York University have revealed how super-enhancers work to increase gene expression of the α-globin gene.

Mapping proteins in brain tumours to help understand cancer

A group of researchers led by Dr Roman Fischer at NDM’s Target Discovery Institute, Centre for Medicines Discovery (CMD) and CAMS Oxford Institute Principal Investigator has developed a method to study proteins in human tumours by creating detailed maps that show how much of each protein is present in different parts of the tissue.

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

A Nature Communications study led by Professor Ling-Pei Ho’s group provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.

Fighting Back Against Viral Evasion of Host Defences

In new research, published in Nature, Professor Geoffrey L Smith and team identify a mechanism by which poxviruses evade host immune defences, opening up new avenues for therapies using existing licensed drugs.

COVID-19 Impact Report

The CAMS-Oxford Institute (COI) has funded 12 COVID-19 projects aiming to understand immune responses to COVID-19, contributing nearly 100 published research articles to the field. Read about the impact the COI has had on our understanding of COVID-19 pathology and immunology.

Taking the non-classical route in the fight against SARS-CoV-2 infection

Researchers from across the Nuffield Department of Medicine, including many from the CAMS-Oxford Institute, have published a new article in Science Immunology investigating the role of HLA-E-restricted SARS-CoV-2-specific T cells.

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

New research published in Nature Immunology showcases the collaborative efforts of CAMS Oxford Institute researchers to describe a novel pairing of integrins which could improve T cell control of cancer.

Cutting through the fat to understand how lipids influence immune responses

An international team of scientists, including CAMS Oxford Institute group leaders Prof. Graham Ogg & Dr Yi-Ling Chen, have developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.

About

The Chinese Academy of Medical Sciences Oxford Institute (COI) is China’s first medical sciences institute in the UK, hosted by University of Oxford. It is a collaboration between the Chinese Academy of Medical Sciences (CAMS) and the University. Combining the strengths of both partners - the Institute aims to deliver outstanding science to help develop innovative medicines to tackle infectious diseases and cancer.

Seminars

Treg targeting reprograms the innate and adaptive immune microenvironment in brain cancer

Tuesday, 04 February 2025, 9.30am to 10.30am

Speakers: Dr. Felipe Galvez-Cancino

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Mapping proteins in brain tumours to help understand cancer

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

Fighting Back Against Viral Evasion of Host Defences

COVID-19 Impact Report

Taking the non-classical route in the fight against SARS-CoV-2 infection

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

Cutting through the fat to understand how lipids influence immune responses

About

News

New funding to create a Lymphoid Organoid and Explant Hub received from NC3Rs

Adán Pinto-Fernández wins a 2024 OCION Pump Prime Award

University of Oxford unveils new vaccine development partnership

Seminars

Treg targeting reprograms the innate and adaptive immune microenvironment in brain cancer

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Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

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Follow

News

New funding to create a Lymphoid Organoid and Explant Hub received from NC3Rs

Adán Pinto-Fernández wins a 2024 OCION Pump Prime Award

University of Oxford unveils new vaccine development partnership

Seminars

Treg targeting reprograms the innate and adaptive immune microenvironment in brain cancer