COI Publications

COI affiliated Publications in 2020/2021

The antigenic anatomy of SARS-CoV-2 receptor binding domain

GUPTA S. et al, (2021), Cell

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Ewer KJ. et al, (2021), Nature Medicine, 27, 270 - 278

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.

Tan TK. et al, (2021), Nature communications, 12

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Barrett JR. et al, (2021), Nature Medicine, 27, 279 - 288

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

Ramasamy MN. et al, (2020), The Lancet, 396, 1979 - 1993

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity.

Pinto-Fernandez A. et al, (2020), British journal of cancer

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

Peng Y. et al, (2020), Nature Immunology, 21, 1336 - 1345

Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Kanellakis NI. et al, (2020), Thorax, 75, 1004 - 1008

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients

DONG T., (2020), BioRxiv

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

Zhou D. et al, (2020), Nature Structural & Molecular Biology, 27, 950 - 958

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

Huo J. et al, (2020), Nature Structural & Molecular Biology, 27, 846 - 854

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Fenech EJ. et al, (2020), eLife, 9

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Huo J. et al, (2020), Cell Host & Microbe, 28, 445 - 454.e6

Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease.

Zhao Y. et al, (2020), JCI insight, 5

Clinical and epidemiological features of COVID-19 family clusters in Beijing, China.

Song R. et al, (2020), The Journal of infection, 81, e26 - e30

IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models.

Forbester JL. et al, (2020), Journal of virology, 94

Deep analysis of the USP18-dependent ISGylome and proteome unveils important roles for USP18 in tumour cell antigenicity and radiosensitivity

Pinto-Fernandez A. et al, (2020)

Defective Interferon Gamma Production by Tumor-Specific CD8+ T Cells Is Associated With 5′Methylcytosine-Guanine Hypermethylation of Interferon Gamma Promoter

Abd Hamid M. et al, (2020), Frontiers in Immunology, 11

Self-Maintaining CD103+ Cancer-Specific T Cells Are Highly Energetic with Rapid Cytotoxic and Effector Responses

Abd Hamid M. et al, (2020), Cancer Immunology Research, 8, 203 - 216

Broadly inhibiting anti-neuraminidase monoclonal antibodies induced by 1 trivalent influenza vaccine and H7N9 infection in humans

RIJAL P. and TOWNSEND A., (2019), Journal of Virology

A Comprehensive Analysis of Key Immune Checkpoint Receptors on Tumor-Infiltrating T Cells From Multiple Types of Cancer

Li X. et al, (2019), Frontiers in Oncology, 9

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

Saliba DG. et al, (2019), eLife, 8

Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study.

Lindsey BB. et al, (2019), The Lancet. Respiratory medicine, 7, 665 - 676

Enriched HLA-E and CD94/NKG2A Interaction Limits Antitumor CD8+ Tumor-Infiltrating T Lymphocyte Responses

Abd Hamid M. et al, (2019), Cancer Immunology Research, 7, 1293 - 1306

From herbal small RNAs to one medicine.

Ji C. et al, (2019), Sci China Life Sci

Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans

Huang K-YA. et al, (2019), Nature Microbiology, 4, 306 - 315

IFITM3: How genetics influence influenza infection demographically.

Wellington D. et al, (2019), Biomedical journal, 42, 19 - 26

Biological effect of tissue plasminogen activator (t-PA) and DNase intrapleural delivery in pleural infection patients.

Kanellakis NI. et al, (2019), BMJ open respiratory research, 6

Survival And Pleurodesis Response Markers In Malignant Pleural Effusion-The Promise Study

Psallidas I. et al, (2018), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197

Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis

Psallidas I. et al, (2018), The Lancet Oncology, 19, 930 - 939