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Cutting through the fat to understand how lipids influence immune responses

An international team of scientists, including CAMS Oxford Institute group leaders Prof. Graham Ogg & Dr Yi-Ling Chen, have developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.

Fighting Back Against Viral Evasion of Host Defences

In new research, published in Nature, Professor Geoffrey L Smith and team identify a mechanism by which poxviruses evade host immune defences, opening up new avenues for therapies using existing licensed drugs.

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Researchers from Oxford University & New York University have revealed how super-enhancers work to increase gene expression of the α-globin gene.

Mapping proteins in brain tumours to help understand cancer

A group of researchers led by Dr Roman Fischer at NDM’s Target Discovery Institute, Centre for Medicines Discovery (CMD) and CAMS Oxford Institute Principal Investigator has developed a method to study proteins in human tumours by creating detailed maps that show how much of each protein is present in different parts of the tissue.

COVID-19 Impact Report

The CAMS-Oxford Institute (COI) has funded 12 COVID-19 projects aiming to understand immune responses to COVID-19, contributing nearly 100 published research articles to the field. Read about the impact the COI has had on our understanding of COVID-19 pathology and immunology.

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

New research published in Nature Immunology showcases the collaborative efforts of CAMS Oxford Institute researchers to describe a novel pairing of integrins which could improve T cell control of cancer.

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

A Nature Communications study led by Professor Ling-Pei Ho’s group provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.

Taking the non-classical route in the fight against SARS-CoV-2 infection

Researchers from across the Nuffield Department of Medicine, including many from the CAMS-Oxford Institute, have published a new article in Science Immunology investigating the role of HLA-E-restricted SARS-CoV-2-specific T cells.

COI Spatial Profiling Hub receives formal accreditation as a Bruker Academic Partner

We’re pleased to announce that the CAMS Oxford Institute Spatial and Gene Profiling Hub has been formally recognized by Bruker Spatial Biology for its generation of high-quality spatial transcriptomic and proteomic data across its nCounter® and GeoMx® Digital Spatial Profiler platforms.

About

The Chinese Academy of Medical Sciences Oxford Institute (COI) is China’s first medical sciences institute in the UK, hosted by University of Oxford. It is a collaboration between the Chinese Academy of Medical Sciences (CAMS) and the University. Combining the strengths of both partners - the Institute aims to deliver outstanding science to help develop innovative medicines to tackle infectious diseases and cancer.

Seminars

Title TBC

Tuesday, 15 April 2025, 9.30am to 10.30am

Speakers: Prof Eric O'Neill

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 29 April 2025, 9.30am to 10.30am

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 13 May 2025, 9.30am to 10.30am

Speakers: Prof Andy Sewell

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 27 May 2025, 9.30am to 10.30am

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
A Postcard from my Journey with the T cell Receptor

Tuesday, 10 June 2025, 9.30am to 11am

Speakers: Prof. Chris Garcia

Venue: Richard Doll Building, Old Road Campus OX3 7LF

Cutting through the fat to understand how lipids influence immune responses

Fighting Back Against Viral Evasion of Host Defences

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Mapping proteins in brain tumours to help understand cancer

COVID-19 Impact Report

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

Taking the non-classical route in the fight against SARS-CoV-2 infection

COI Spatial Profiling Hub receives formal accreditation as a Bruker Academic Partner

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COI Spatial Profiling Hub receives formal accreditation as a Bruker Academic Partner

Matthew Bottomley: The Latest Winner in CRUK’s ‘Research is Beautiful’ Campaign

Researchers develop new method to identify fake Covid-19 vaccines

Seminars

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Title TBC

A Postcard from my Journey with the T cell Receptor

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Cutting through the fat to understand how lipids influence immune responses

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