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Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

New research published in Nature Immunology showcases the collaborative efforts of CAMS Oxford Institute researchers to describe a novel pairing of integrins which could improve T cell control of cancer.

COVID-19 Impact Report

The CAMS-Oxford Institute (COI) has funded 12 COVID-19 projects aiming to understand immune responses to COVID-19, contributing nearly 100 published research articles to the field. Read about the impact the COI has had on our understanding of COVID-19 pathology and immunology.

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

A Nature Communications study led by Professor Ling-Pei Ho’s group provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.

Cutting through the fat to understand how lipids influence immune responses

An international team of scientists, including CAMS Oxford Institute group leaders Prof. Graham Ogg & Dr Yi-Ling Chen, have developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.

Fighting Back Against Viral Evasion of Host Defences

In new research, published in Nature, Professor Geoffrey L Smith and team identify a mechanism by which poxviruses evade host immune defences, opening up new avenues for therapies using existing licensed drugs.

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Researchers from Oxford University & New York University have revealed how super-enhancers work to increase gene expression of the α-globin gene.

COI Spatial Profiling Hub receives formal accreditation as a Bruker Academic Partner

We’re pleased to announce that the CAMS Oxford Institute Spatial and Gene Profiling Hub has been formally recognized by Bruker Spatial Biology for its generation of high-quality spatial transcriptomic and proteomic data across its nCounter® and GeoMx® Digital Spatial Profiler platforms.

Taking the non-classical route in the fight against SARS-CoV-2 infection

Researchers from across the Nuffield Department of Medicine, including many from the CAMS-Oxford Institute, have published a new article in Science Immunology investigating the role of HLA-E-restricted SARS-CoV-2-specific T cells.

CAMS Oxford Institute Network Day Held at Richard Doll Building on 6 June 2025

The CAMS Oxford Institute (COI) held its 2025 Network Day on 6 June at the Richard Doll Building, bringing together researchers, clinicians, and collaborators for a day of scientific exchange, collaborative reflection, and discussion on the future of translational immunology. The programme featured a rich mix of talks, poster presentations, and networking sessions designed to highlight both established research strengths and emerging voices across the COI community.

Mapping proteins in brain tumours to help understand cancer

A group of researchers led by Dr Roman Fischer at NDM’s Target Discovery Institute, Centre for Medicines Discovery (CMD) and CAMS Oxford Institute Principal Investigator has developed a method to study proteins in human tumours by creating detailed maps that show how much of each protein is present in different parts of the tissue.

About

The Chinese Academy of Medical Sciences Oxford Institute (COI) is China’s first medical sciences institute in the UK, hosted by University of Oxford. It is a collaboration between the Chinese Academy of Medical Sciences (CAMS) and the University. Combining the strengths of both partners - the Institute aims to deliver outstanding science to help develop innovative medicines to tackle infectious diseases and cancer.

Seminars

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Tuesday, 09 September 2025, 9.30am to 10.30am

Speakers: Prof Christopher Buckley

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
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Tuesday, 23 September 2025, 9.30am to 10.30am

Speakers: Dr Marco Fritzsche

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 07 October 2025, 9.30am to 10.30am

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 28 October 2025, 9.30am to 10.30am

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 11 November 2025, 9.30am to 10.30am

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

COVID-19 Impact Report

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

Cutting through the fat to understand how lipids influence immune responses

Fighting Back Against Viral Evasion of Host Defences

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

COI Spatial Profiling Hub receives formal accreditation as a Bruker Academic Partner

Taking the non-classical route in the fight against SARS-CoV-2 infection

CAMS Oxford Institute Network Day Held at Richard Doll Building on 6 June 2025

Mapping proteins in brain tumours to help understand cancer

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John Fell Fund Supports New Study Exploring Skin Immunity in Kidney Disease Patients

Unveiling the mystery: Scientists Reveal the Determinants That Control the Nuclear Import of HIV-1

Visualising the SARS-CoV-2 Fusion Process and Its Inhibition Under Near-Native Conditions Using Cryo-Electron Tomography

Seminars

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Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

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