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Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

New research published in Nature Immunology showcases the collaborative efforts of CAMS Oxford Institute researchers to describe a novel pairing of integrins which could improve T cell control of cancer.

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

A Nature Communications study led by Professor Ling-Pei Ho’s group provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.

Taking the non-classical route in the fight against SARS-CoV-2 infection

Researchers from across the Nuffield Department of Medicine, including many from the CAMS-Oxford Institute, have published a new article in Science Immunology investigating the role of HLA-E-restricted SARS-CoV-2-specific T cells.

COVID-19 Impact Report

The CAMS-Oxford Institute (COI) has funded 12 COVID-19 projects aiming to understand immune responses to COVID-19, contributing nearly 100 published research articles to the field. Read about the impact the COI has had on our understanding of COVID-19 pathology and immunology.

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Researchers from Oxford University & New York University have revealed how super-enhancers work to increase gene expression of the α-globin gene.

Cutting through the fat to understand how lipids influence immune responses

An international team of scientists, including CAMS Oxford Institute group leaders Prof. Graham Ogg & Dr Yi-Ling Chen, have developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.

Mapping proteins in brain tumours to help understand cancer

A group of researchers led by Dr Roman Fischer at NDM’s Target Discovery Institute, Centre for Medicines Discovery (CMD) and CAMS Oxford Institute Principal Investigator has developed a method to study proteins in human tumours by creating detailed maps that show how much of each protein is present in different parts of the tissue.

Fighting Back Against Viral Evasion of Host Defences

In new research, published in Nature, Professor Geoffrey L Smith and team identify a mechanism by which poxviruses evade host immune defences, opening up new avenues for therapies using existing licensed drugs.

About

The Chinese Academy of Medical Sciences Oxford Institute (COI) is China’s first medical sciences institute in the UK, hosted by University of Oxford. It is a collaboration between the Chinese Academy of Medical Sciences (CAMS) and the University. Combining the strengths of both partners - the Institute aims to deliver outstanding science to help develop innovative medicines to tackle infectious diseases and cancer.

Seminars

Title TBC

Tuesday, 15 October 2024, 9.30am to 10.30am

Speakers: Dr Katherine Bull

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 29 October 2024, 9.30am to 10.30am

Speakers: Prof. Charlotte Deane

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Selection events shaping serum antibody responses to infection

Tuesday, 05 November 2024, 9.30am to 10.30am

Speakers: Oliver Bannard

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Title TBC

Tuesday, 19 November 2024, 9.30am to 10.30am

Speakers: Dr Xinxue Liu

Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Activation of Inhibitory Receptors on Mast cells: Is it a Winning Strategy to Fight Allergic Diseases and Mastocytosis?

Monday, 09 December 2024, 12pm to 1pm

Speakers: Prof. Francesca Levi-Schaffer

Venue: Richard Doll Building, Old Road Campus OX3 7LF

Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

Single cell spatial analysis provides new insight into immune-pathology in COVID-19 lungs

Taking the non-classical route in the fight against SARS-CoV-2 infection

COVID-19 Impact Report

Super-Enhancer Components Work as a Team to Increase Gene Expression of Alpha-globin

Cutting through the fat to understand how lipids influence immune responses

Mapping proteins in brain tumours to help understand cancer

Fighting Back Against Viral Evasion of Host Defences

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News

Adán Pinto-Fernández Secures Prestigious 2-Year Grant from Boehringer Ingelheim

ORTU awarded £2.8m to study treatment for pleural infection

Peijun Zhang elected to European Molecular Biology Organization membership

Seminars

Title TBC

Title TBC

Selection events shaping serum antibody responses to infection

Title TBC

Activation of Inhibitory Receptors on Mast cells: Is it a Winning Strategy to Fight Allergic Diseases and Mastocytosis?

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Novel pairing of integrins improves action of T cells on cancer cells to control tumour growth

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