Contact information
Research groups
Websites
-
MRC Human Immunology Unit
Research Unit
-
MRC Weatherall Institute of Molecular Medicine
Research Institute
Graham Ogg
Professor of Dermatology
Skin immunology; T cells; innate lymphoid cells
Skin and mucosae frequently represent the first point of contact with pathogens and allergens, yet we still know relatively little of the role of the surface immune system in clearing such challenges. This is crucially important in understanding the mechanisms of skin diseases and related diseases, and for optimising approaches to cutaneous drug and vaccine delivery. The aim of the group is therefore to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.
Recent publications
-
Innate Lymphocyte Mechanisms in Skin Diseases.
Book
Chen Y-L. et al, (2020), 38, 171 - 202
-
Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation
Journal article
Chen Y-L. et al, (2020), The Journal of Experimental Medicine, 217
-
Natural killer cells get under your skin.
Journal article
Ogg G., (2020), Science translational medicine, 12
-
Association of dengue virus-specific polyfunctional T-cell responses with clinical disease severity in acute dengue infection.
Journal article
Wijeratne DT. et al, (2019), Immunity, inflammation and disease, 7, 276 - 285
-
Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells.
Journal article
Luo J. et al, (2019), The Journal of allergy and clinical immunology, 144, 1722 - 1726.e10