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This theme addresses fundamental questions about cell-cell signalling systems of importance to human health. Such as, how are signalling assemblies arranged? Which features are necessary for normal signal transduction into the cell? What mechanisms trigger dysfunctional signalling? The work ties into an extensive network of interdisciplinary local and international collaborations with the ultimate aim of learning how to manipulate these signalling systems for the design of new clinical therapies.

THEME LEADERS

Yvonne Jones

Zihe Rao

PRINCIPAL INVESTIGATORS

Dave Stuart