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COI Investigators Reported a Comprehensive Analysis of Key Immune Checkpoint Receptors on Tumor-Infiltrating T Cells From Multiple Types of Cancer

18 November 2019

COI Investigators (Xi Li, Ruozheng Wang are the joint first authors) reported a comprehensive analysis of key immune checkpoint receptors on T cells in 172 treatment-naïve, primary cancer patients from the eight most prevalent types of cancer.

They have evaluated the expression of inhibitory receptors on tumor infiltrating T cells and paired blood samples from 172 primary cancer patients for their potential value in checkpoint blockade and their risk for causing autoimmune disease.

(Li, et al, Frontiers in Oncology)