Publications for all Oxford Principal Investigators within the CAMS Oxford Institute are included here, please use the search functions for publications related to specific Principal Investigators.
ADAR1: from basic mechanisms to inhibitors.
Rehwinkel J. and Mehdipour P., (2024), Trends in cell biology
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels
Blest HTW. et al, (2024), Cell Reports, 43, 114122 - 114122
ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice.
Roderick-Richardson JE. et al, (2024), Proc Natl Acad Sci U S A, 121
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.
Đukić N. et al, (2023), Science advances, 9
The Z-nucleic acid sensor ZBP1 in health and disease.
Maelfait J. and Rehwinkel J., (2023), The Journal of experimental medicine, 220
Single-cell analysis of signalling and transcriptional responses to type I interferons
Rigby R. et al, (2023)
The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses.
Serrero MC. et al, (2022), eLife, 11
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Moll T. et al, (2022), bioRxiv
Neutrophilia, lymphopenia and myeloid dysfunction: a living review of the quantitative changes to innate and adaptive immune cells which define COVID-19 pathology
Codd AS. et al, (2021), Oxford Open Immunology, 2
SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination.
Husain A. et al, (2020), The EMBO journal
Enhanced immunogenicity of mitochondrial-localized proteins in cancer cells.
Prota G. et al, (2020), Cancer Immunol Res
RIG-I-like receptors: their regulation and roles in RNA sensing.
Rehwinkel J. and Gack MU., (2020), Nat Rev Immunol
Type-1 IFN primed monocytes in pathogenesis of idiopathic pulmonary fibrosis
Fraser E. et al, (2020)
Nucleic Acid Sensors and Programmed Cell Death
Maelfait J. et al, (2019), Journal of Molecular Biology
PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection.
Rigby RE. et al, (2019), Scientific reports, 9, 7216 - 7216