Publications for all Oxford Principal Investigators within the CAMS Oxford Institute are included here, please use the search functions for publications related to specific Principal Investigators.
HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus.
Lu Y. et al, (2024), Cell reports, 43
Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4.
Georgana I. et al, (2024), J Virol
Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Albarnaz JD. et al, (2023), Nature communications, 14
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
Stewart H. et al, (2023), iScience, 26, 108080 - 108080
TRIM5α restricts poxviruses and is antagonized by CypA and viral protein C6
Smith G., (2023), Nature
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination
Yin Z. et al, (2023), Cell Reports, 42, 112470 - 112470
Transcriptional reprogramming of natural killer cells by vaccinia virus shows both distinct and conserved features with mCMV
Depierreux DM. et al, (2023), Frontiers in Immunology, 14
Suppression of innate immunity by the vaccinia virus protein N1 promotes skin microbiota expansion and increased immune infiltration following vaccination
Shmeleva EV. et al, (2022), Journal of General Virology, 103
Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins
Lu Y. et al, (2022), Frontiers in Microbiology, 13
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
Stewart H. et al, (2022)
Vaccinia virus BTB-Kelch proteins C2 and F3 inhibit NF-κB activation
Zhang R-Y. et al, (2022), Journal of General Virology, 103
Quantitative temporal analysis of modified vaccinia Ankara, the monkeypox and smallpox vaccine
Albarnaz JD. et al, (2022)
Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies
Depierreux DM. et al, (2022), PLOS Pathogens, 18, e1010612 - e1010612
Dysregulation of Cellular VRK1, BAF, and Innate Immune Signaling by the Vaccinia Virus B12 Pseudokinase
Linville AC. et al, (2022), Journal of Virology, 96
Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response
Shmeleva EV. et al, (2022), PLOS Pathogens, 18, e1009854 - e1009854
Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling
Talbot-Cooper C. et al, (2022), Cell Host & Microbe, 30, 357 - 372.e11
The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling
Torres AA. et al, (2022), PLOS Pathogens, 18, e1010277 - e1010277
DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation
Pallett M. et al, (2022), Viruses, 14, 316 - 316
The crystal structure of vaccinia virus protein E2 and perspectives on the prediction of novel viral protein folds
Gao WND. et al, (2022), Journal of General Virology, 103