Publications for all Oxford Principal Investigators within the CAMS Oxford Institute are included here, please use the search functions for publications related to specific Principal Investigators.
Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
Journal article
Zhao Y. et al, (2020), Nature Communications, 11
Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility.
Journal article
Rozbesky D. et al, (2020), Structure (London, England : 1993)
The guidance receptor plexin D1 is a mechanosensor in endothelial cells.
Journal article
Mehta V. et al, (2020), Nature, 578, 290 - 295
Structural characterisation of melatonin as an inhibitor of the Wnt deacylase Notum.
Journal article
Zhao Y. et al, (2019), J Pineal Res
Cell guidance ligands, receptors and complexes - orchestrating signalling in time and space.
Journal article
Rozbesky D. and Jones EY., (2019), Curr Opin Struct Biol, 61, 79 - 85
Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells
Journal article
Barnkob MB. et al, (2019)
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.
Journal article
Atkinson BN. et al, (2019), Bioorganic & medicinal chemistry letters
Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning
Journal article
ROZBESKY D. et al, (2019), Nature Communications
Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning
Journal article
ROZBESKY D. et al, (2019), Nature Communications
iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition
Journal article
LU XIN., (2019), Proceedings of the National Academy of Sciences
Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.
Journal article
van der Klaauw AA. et al, (2019), Cell
Designer protein delivers signal of choice.
Journal article
Jones EY., (2019), Nature, 565, 165 - 166
Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen
Journal article
Atkinson BN. et al, (2019), MedChemComm, 10, 1361 - 1369
Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding
Journal article
Walters LC. et al, (2018), Nature Communications, 9
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding
Journal article
Walters LC. et al, (2018), Nature Communications, 9
Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins.
Journal article
Elegheert J. et al, (2018), Nat Protoc
Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational change and cause signalling bias.
Journal article
Gorvin CM. et al, (2018), Hum Mol Genet, 27, 3720 - 3733
Structural biology and the molecular mechanics of cell guidance signalling
Conference paper
Jones EY., (2018), FEBS OPEN BIO, 8, 57 - 57
A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin-biased signaling.
Journal article
Gorvin CM. et al, (2018), Sci Signal, 11
A Calcium-Sensing Receptor (CASR) Mutation Causes Hypocalcemia by Disrupting a Transmembrane Salt Bridge that Modulates beta-arrestin Signaling.
Conference paper
Gorvin C. et al, (2017), JOURNAL OF BONE AND MINERAL RESEARCH, 32, S133 - S133