Publications for all Oxford Principal Investigators within the CAMS Oxford Institute are included here, please use the search functions for publications related to specific Principal Investigators.
Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation
Preprint
Stolper RJ. et al, (2023)
Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α-globin locus.
Journal article
Kassouf M. et al, (2023), Bioessays
Scalable in vitro production of defined mouse erythroblasts.
Journal article
Francis HS. et al, (2022), PloS one, 17
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis.
Journal article
Xiang G. et al, (2020), Genome research
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus
Journal article
Oudelaar AM. et al, (2019), Nature Communications, 10
An integrated platform to systematically identify causal variants and genes for polygenic human traits
Journal article
Downes DJ. et al, (2019)
The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.
Journal article
van Bemmel JG. et al, (2019), Nature genetics
Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate.
Journal article
Palii CG. et al, (2019), Cell Stem Cell, 24, 812 - 820.e5
How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.
Journal article
Truch J. et al, (2019), Methods in molecular biology (Clifton, N.J.), 1832, 105 - 130
The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.
Journal article
Young CC. et al, (2019), Cell Mol Gastroenterol Hepatol, 7, 93 - 113
Potential new approaches to the management of the Hb Bart's hydrops fetalis syndrome: the most severe form of α-thalassemia.
Journal article
King AJ. and Higgs DR., (2018), Hematology Am Soc Hematol Educ Program, 2018, 353 - 360
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.
Journal article
Oudelaar AM. et al, (2018), Nat Genet
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.
Journal article
Brown JM. et al, (2018), Nat Commun, 9
Robust CRISPR/Cas9 Genome Editing of the HUDEP-2 Erythroid Precursor Line Using Plasmids and Single Stranded Oligonucleotide Donors
Journal article
BABBS C. et al, (2018), Methods and Protocols
Anaemia among females in child-bearing age: Relative contributions, effects and interactions of α- and β-thalassaemia.
Journal article
Mettananda S. et al, (2018), PLoS One, 13
Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C.
Journal article
Oudelaar AM. et al, (2017), Nucleic Acids Res, 45
Between form and function: the complexity of genome folding.
Journal article
Oudelaar AM. et al, (2017), Hum Mol Genet, 26, R208 - R215
Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints.
Journal article
Schwessinger R. et al, (2017), Genome research, 27, 1730 - 1742
Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.
Journal article
Hanssen LLP. et al, (2017), Nature cell biology, 19, 952 - 961
A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemias.
Journal article
Roy NB. et al, (2016), British journal of haematology, 175, 318 - 330