Publications for all Oxford Principal Investigators within the CAMS Oxford Institute are included here, please use the search functions for publications related to specific Principal Investigators.
Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future.
Journal article
Amid A. et al, (2024), Blood
Super-enhancers include classical enhancers and facilitators to fully activate gene expression.
Journal article
Blayney JW. et al, (2023), Cell
Active regulatory elements recruit cohesin to establish cell-specific chromatin domains
Preprint
Georgiades E. et al, (2023)
Ancient genomic linkage couples metabolism with erythroid development.
Journal article
Preston AE. et al, (2023), bioRxiv
Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation
Preprint
Stolper RJ. et al, (2023)
RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.
Journal article
Martell DJ. et al, (2023), Developmental cell
Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α-globin locus.
Journal article
Kassouf M. et al, (2023), Bioessays
The characteristics of CTCF binding sequences contribute to enhancer blocking activity
Preprint
Tsang F. et al, (2023)
P104: BASE EDITING REPAIRS THE HBE MUTATION RESTORING THE PRODUCTION OF NORMAL GLOBIN CHAINS IN SEVERE HBE/β-THALASSEMIA PATIENT HEMATOPOIETIC STEM AND ERYTHROID CELLS
Journal article
Badat M. et al, (2022), HemaSphere, 6, 19 - 20
An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis
Conference paper
Preston AE. et al, (2022), BLOOD, 140
Multipartite super-enhancers function in an orientation-dependent manner
Journal article
Kassouf M. et al, (2022)
Scalable in vitro production of defined mouse erythroblasts.
Journal article
Francis HS. et al, (2022), PloS one, 17
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis.
Journal article
Xiang G. et al, (2020), Genome research
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus
Journal article
Oudelaar AM. et al, (2019), Nature Communications, 10
An integrated platform to systematically identify causal variants and genes for polygenic human traits
Journal article
Downes DJ. et al, (2019)
The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.
Journal article
van Bemmel JG. et al, (2019), Nature genetics
Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate.
Journal article
Palii CG. et al, (2019), Cell Stem Cell, 24, 812 - 820.e5
How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.
Journal article
Truch J. et al, (2019), Methods in molecular biology (Clifton, N.J.), 1832, 105 - 130
The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.
Journal article
Young CC. et al, (2019), Cell Mol Gastroenterol Hepatol, 7, 93 - 113
Potential new approaches to the management of the Hb Bart's hydrops fetalis syndrome: the most severe form of α-thalassemia.
Journal article
King AJ. and Higgs DR., (2018), Hematology Am Soc Hematol Educ Program, 2018, 353 - 360