Publications for all Oxford Principal Investigators within the CAMS Oxford Institute are included here, please use the search functions for publications related to specific Principal Investigators.
Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP30
Damianou A. et al, (2025), Cell Chemical Biology
Deubiquitinases in muscle physiology and disorders
Olie CS. et al, (2024), Biochemical Society Transactions, 52, 1085 - 1098
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex
Damianou A. et al, (2024), Life Science Alliance, 7, e202302245 - e202302245
Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia
Liang Z. et al, (2024), Cell Reports, 43, 114152 - 114152
USP18 is an essential regulator of muscle cell differentiation and maturation
Olie CS. et al, (2023), Cell Death & Disease, 14
USP18 is an essential regulator of muscle cell differentiation and maturation
Olie CS. et al, (2022)
Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection
Munnur D. et al, (2021), Nature Immunology, 22, 1416 - 1427
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
Ruiz EJ. et al, (2021), eLife, 10
Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities
Liang Z. et al, (2021), Cell Communication and Signaling, 19
Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity
Pinto-Fernandez A. et al, (2021), British Journal of Cancer, 124, 817 - 830
Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex.
Burge RJ. et al, (2020), PLoS pathogens, 16
Essential roles for deubiquitination in Leishmania life cycle progression.
Damianou A. et al, (2020), PLoS pathogens, 16
Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics
Pinto-Fernández A. et al, (2019), Frontiers in Chemistry, 7
Pneumococcal galactose catabolism is controlled by multiple regulators acting on pyruvate formate lyase
Al-Bayati FAY. et al, (2017), Scientific Reports, 7