Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

© Springer International Publishing AG 2017. All rights reserved. Neuropilin functions as a co-receptor for multiple cell surface signalling systems; in particular it regulates VEGF and semaphorin signalling through their respective receptors. The molecular characteristics of neuropilin, the VEGF and semaphorin signalling complexes and their multiple interaction modes have been extensively investigated by structural and biophysical analyses. Much has been learned about the molecular mechanisms by which neuropilin acts as an interaction hub, but the complexities of neuropilin function still pose many questions.

Original publication

DOI

10.1007/978-3-319-48824-0_2

Type

Chapter

Book title

The Neuropilins: Role and Function in Health and Disease

Publication Date

06/02/2017

Pages

9 - 21