Correlates of T-cell–mediated viral control and phenotype of CD8+ T cells in HIV-2, a naturally contained human retroviral infection
de Silva TI., Peng Y., Leligdowicz A., Zaidi I., Li L., Griffin H., Blais M-E., Vincent T., Saraiva M., Yindom L-M., van Tienen C., Easterbrook P., Jaye A., Whittle H., Dong T., Rowland-Jones SL.
Key PointsHIV-2 viral control is associated with a polyfunctional Gag-specific CD8+ T-cell response but not with perforin upregulation. Our findings provide insight into cellular immune responses associated with a naturally contained human retroviral infection.