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This study describes the first case of extensively drug-resistant tuberculosis (XDR-TB) in the Thames Valley and South East Region and discuss the public health implications, highlighting the need to integrate current epidemiological knowledge with clinical expertise in order to diagnose drug-resistant tuberculosis (TB) early. The management of the XDR-TB patients is challenging with few treatment options, expensive therapy, side effects of drugs and a longer course of the treatment.

Original publication

DOI

10.1016/j.jiph.2011.06.003

Type

Journal article

Journal

J Infect Public Health

Publication Date

2011

Volume

4

Pages

207 - 210

Keywords

Adult Antitubercular Agents/pharmacology Contact Tracing/*methods *Drug Resistance, Multiple, Bacterial Extensively Drug-Resistant Tuberculosis/*diagnosis/epidemiology/microbiology/prevention & control Great Britain/epidemiology Humans Mass Screening/*methods Mycobacterium tuberculosis/classification/drug effects/*genetics Population Surveillance Public Health Young Adult