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BackgroundWomen who live with disadvantages such as socioeconomic deprivation, substance misuse, poor mental health, or domestic abuse face inequalities in health before, during, and after pregnancy and for their infants through to childhood. Women do not experience these factors alone; they accumulate and interact. Therefore, there is a need for an overview of interventions that work across health and social care and target women at risk of inequalities in maternal or child health.MethodsSystematic review methodology will be used to identify systematic reviews from high-income countries that describe interventions aiming to reduce inequalities for women who experience social disadvantage during pregnancy. We will describe the range of interventions and their effectiveness in reducing inequalities in maternal or child health. Any individual, hospital, or community-level activity specific to women during the pre-conception, antenatal, or postpartum period up to 1 year after birth will be included, regardless of the setting in which they are delivered. We will search eight electronic databases with the pre-determined search strategy and supplement them with extensive grey literature searches. We will present a narrative synthesis, taking into account the quality assessment and coverage of included studies.DiscussionInequalities in maternal and child health are a key priority area for national policymakers. Understanding the range and effectiveness of interventions across the perinatal period will inform policy and practice. Identifying gaps in the evidence will inform future research.Systematic review registrationPROSPERO CRD42023455502.

Original publication




Journal article


Systematic reviews

Publication Date





Department of Population Health, National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, NuffieldHeadington, Oxford, OX3 7LF, UK.


Humans, Pregnancy, Research Design, Developed Countries, Socioeconomic Factors, Pregnant Women, Female, Health Status Disparities, Healthcare Disparities, Maternal Health, Systematic Reviews as Topic