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<jats:p>1. Three non-major histocompatability complex genes, Idd-3, Idd-4 and Idd-5, that influence the onset of autoimmune type 1 diabetes in the non-obese diabetic mouse have been located on chromosomes 3, 11 and 1.</jats:p> <jats:p>2. In undertaking this study, a new map of the mouse genome has been created from polymerase chain reaction-analysable mouse microsatellite markers.</jats:p> <jats:p>3. The homologues of these genes may reside on human chromosomes 1 or 4 (Idd-3), 17 (Idd-4) and 2q (Idd-5).</jats:p>

Original publication

DOI

10.1042/cs0840257

Type

Journal article

Journal

Clinical Science

Publisher

Portland Press Ltd.

Publication Date

01/03/1993

Volume

84

Pages

257 - 262