Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation
Dushek O., Aleksic M., Wheeler RJ., Zhang H., Cordoba S-P., Peng Y-C., Chen J-L., Cerundolo V., Dong T., Coombs D., van der Merwe PA.
Efficient T cell activation depends on the rate with which T cell receptors and antigens bind and unbind, rather than simply their equilibrium affinity.