The staying power of hematopoietic stem cells.

Dustin ML.

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The staying power of hematopoietic stem cells.

Dustin ML.

Hematopoietic stem and progenitor cells (HSPCs) use specialized adhesive structures referred to as magnupodium to stay in hematopoietic niches. Bessey et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202005085) define new characteristics of the magnupodium, including centriole polarization and the necessary and sufficient role of CXCR4 signaling.

Original publication

DOI

10.1083/jcb.202109019

Type

Journal article

Journal

The Journal of cell biology

Publication Date

11/2021

Volume

220

Addresses

Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.

Keywords

Hematopoietic Stem Cells, Centrioles, Signal Transduction