Research groups
Alison Simmons
PhD FRCP FMedSci
Director of the MRC Translational Immune Discovery Unit
- Consultant Physician
- Professor of Gastroenterology
Key publications
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Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis
Journal article
Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15
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Spatiotemporal analysis of human intestinal development at single-cell resolution
Journal article
Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23
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Single-cell atlas of colonic CD8+ T cells in ulcerative colitis
Journal article
Corridoni D. et al, (2020), Nature Medicine, 26, 1480 - 1490
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Colonic epithelial cell diversity in health and inflammatory bowel disease
Journal article
Parikh K. et al, (2019), Nature, 567, 49 - 55
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Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets
Journal article
Aulicino A. et al, (2018), Nature Communications, 9
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Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease
Journal article
Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17
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Snapin promotes HIV ‐1 transmission from dendritic cells by dampening TLR 8 signaling
Journal article
Khatamzas E. et al, (2017), The EMBO Journal, 36, 2998 - 3011
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The Intracellular Sensor NOD2 Induces MicroRNA-29 Expression in Human Dendritic Cells to Limit IL-23 Release
Journal article
Brain O. et al, (2013), Immunity, 39, 521 - 536
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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
Journal article
Cooney R. et al, (2010), Nature Medicine, 16, 90 - 97