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Ying-Chen Lin
Postdoctoral Scientist
Dr. Ying-Chen (Jean) Lin completed her PhD in molecular and cell biology through the Taiwan International Graduate Program at Academia Sinica and National Chung Hsing University, where she investigated phospholipid biosynthesis and lipid-mediated regulation of plant development and stress responses. She then joined the University of Oxford as a Postdoctoral Research Associate in the Department of Biochemistry, focusing on lipid trafficking and membrane contact sites using lipidomics, isotope labelling, microscopy, and biochemical approaches. She is currently a Postdoctoral Researcher at the CAMS Oxford Institute in the Nuffield Department of Medicine, where she investigates lipid antigens and lipid-mediated metabolic pathways in immune responses and disease.
Lipids are fundamental components of cellular membranes with essential roles in metabolism, signalling, and cellular organisation. Jean's research focuses on lipid biology at the interface of immunology and disease, with particular interest in CD1c-mediated lipid antigen presentation in the context of Group A Streptococcus (GAS) infection and associated autoimmune conditions. By combining advanced lipidomics, in vitro functional immunological assays, and in vivo models, she aims to uncover how lipid antigens and lipid-mediated immune pathways contribute to host responses and disease pathogenesis.