Simin Yu
DPhil Student
Research Interests
My work centres on respiratory medicine, with a particular focus on T-cell–mediated pathways in airway diseases, especially asthma. During my DPhil, I am supervised by Prof. Ian Pavord, Dr. Jian Luo and Prof. Luzheng Xue. I aim to understand how Type-2 immunity shapes disease progression and therapeutic response. My approach integrates multi-omics sequencing, functional immunology, and population-level clinical datasets to generate mechanistic insight with translational relevance. By combining computational analysis with experimental and clinical cohorts, I hope to define immune signatures that can guide precision medicine in respiratory disease.
Background
I completed the eight-year medical programme at West China School of Medicine, obtaining my bachelor’s degree in 2024. Before joining Oxford, my research centred on bioinformatics and population-health–oriented disease studies, where I applied high-throughput data analysis to identify molecular patterns associated with human health outcomes. This foundation in both computational and clinical research now supports my current focus on respiratory immunology and translational systems medicine.