Contact information
Research groups
Mariana Pereira Pinho
Postdoctoral Researcher
Tumor-specific T cell response
My research focuses on the analysis of T cells capable of recognizing and reacting to tumor antigens. Specifically, we are interested in evaluating the specificity and function of tumor-reactive CD8 T cells in breast cancer patients.
Key publications
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Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response
Journal article
Pinho MP. et al, (2019), OncoImmunology, 8, 1607674 - 1607674
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Dendritic cell membrane CD83 enhances immune responses by boosting intracellular calcium release in T lymphocytes
Journal article
Pinho MP. et al, (2014), Journal of Leukocyte Biology, 95, 755 - 762
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Dendritic-tumor cell hybrids induce tumor-specific immune responses more effectively than the simple mixture of dendritic and tumor cells
Journal article
Pinho MP. et al, (2016), Cytotherapy, 18, 570 - 580
Recent publications
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Near-Complete Remission of Glioblastoma in a Patient Treated with an Allogenic Dendritic Cell-Based Vaccine: The Role of Tumor-Specific CD4+T-Cell Cytokine Secretion Pattern in Predicting Response and Recurrence
Journal article
Pinho MP. et al, (2022), International Journal of Molecular Sciences, 23, 5396 - 5396
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HLA‐dependent variation in SARS‐CoV‐2 CD8
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T cell cross‐reactivity with human coronaviruses
Journal article
Buckley PR. et al, (2022), Immunology
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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
Journal article
Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58
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HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses
Journal article
Buckley PR. et al, (2021)
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Potential CD8+ T Cell Cross-Reactivity Against SARS-CoV-2 Conferred by Other Coronavirus Strains
Journal article
Lee CH. et al, (2020), Frontiers in Immunology, 11