A Cell Reports study led by Prof. Benedikt Kessler provides an intricate time-resolved molecular map of different phases of NLRP3 inflammasome activation and unveils ubiquitin C-terminal hydrolase 1 (UCH-L1) as a modulator of NLRP3 inflammasome assembly and IL-1\u03b2 production.
The annual CAMS Oxford Institute Symposium was held on Monday 15th April 2024 in the Richard Doll Building on Old Road Campus for a full day of scientific talks, poster presentations & networking.
New research published in Nature Immunology showcases the collaborative efforts of CAMS Oxford Institute researchers to describe a novel pairing of integrins which could improve T cell control of cancer.
CAMS-Oxford Institute Principal Investigator, Ricardo Fernandes, has been awarded a competitive grant from Cancer Research UK to study anti-tumour T cell responses.
On 1st- 2nd of February 2024, Assistant Professor Yunlong Cao from Peking University, Beijing, China, visited the Chinese Academy of Medical Sciences Oxford Institute (COI), Nuffield Department of Medicine (NDM), University of Oxford.
In a study led by CAMS Researchers, patients were tracked for two years post COVID-19 infection in a bid to understand how memory immune responses decline over time and give insight into vaccination & booster strategies.
Researchers from the CAMS Oxford Institute and NDM Target Discovery Unit, including Prof. Benedikt Kessler and Dr. Ad\u00e1n Pinto-Fern\u00e1ndez, have collaborated with the team of Dr. Paul Geurink and Dr. Aysegul Sapmaz from Leiden University to investigate an important interferon-stimulated gene, ISG15.
A group of researchers led by Dr Roman Fischer at NDM\u2019s Target Discovery Institute, Centre for Medicines Discovery (CMD) and CAMS Oxford Institute Principal Investigator has developed a method to study proteins in human tumours by creating detailed maps that show how much of each protein is present in different parts of the tissue.
A Nature Communications study led by Professor Ling-Pei Ho\u2019s group provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.
An international team of scientists, including CAMS Oxford Institute group leaders Prof. Graham Ogg & Dr Yi-Ling Chen, have developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.
COI Postdoctoral scientist Dr Christina Heroven has been awarded a competitive Early Career Fellowship by the Wellcome Trust, providing funding for five years to support her career progression.
Across Wednesday 20th and Thursday 21st September 2023, a delegation from the Beijing Center for Disease Prevention and Control (Beijing CDC) visited the Chinese Academy of Medical Sciences Oxford Institute (COI), NDM, University of Oxford.
One year on from the launch of the Ling Felce Award for the training of researchers in Oxford, we reflect on the impact of the award and the generosity of our donors.
In new research, published in Nature, Professor Geoffrey L Smith and team identify a mechanism by which poxviruses evade host immune defences, opening up new avenues for therapies using existing licensed drugs.
On Thursday 13th and Friday 14th July 2023, Professor Catherine Wong from Peking Union Medical College Hospital visited Oxford University for the first time as a CAMS Oxford Institute Principal Investigator.
Researchers from across the Nuffield Department of Medicine, including many from the CAMS-Oxford Institute, have published a new article in Science Immunology investigating the role of HLA-E-restricted SARS-CoV-2-specific T cells.
![\"\"](\"https://www.camsoxford.ox.ac.uk/news/nlrp3-inflammasome-201cdubbed201d-by-uch-l1-affecting-il-1b-production-in-macrophages-and-microglia/responsive_image?ratio=r16x9&scale=w760\")
\n \n \n\n\n