The Oxford Respiratory Trials Unit (ORTU) at the Nuffield Department of Medicine has been awarded a \u00a32.8 million grant from the National Institute for Health and Care Research Health Technology Assessment (NIHR HTA) to conduct the MIST4 study.
120 scientists from across Europe and beyond have been elected to the European Molecular Biology Organization (EMBO) membership, an honour that celebrates research excellence and outstanding achievements in the life sciences, including Dr Peijun Zhang from the Nuffield Department of Medicine.
Sepsis patients could be treated based on their immune system\u2019s response to infection, not their symptoms. New research uncovers how different people respond to sepsis based on their genetic makeup, which could help identify who would benefit from certain treatments and lead to the development of targeted therapies.
Globally kidney disease is forecast to be the 5th leading cause of death by 2040, and in the UK more than 3 million people are living with the most severe stages of chronic kidney disease. Chronic kidney disease is often due to autoimmune damage to the filtration units of the kidney, known as the glomeruli, which can occur in lupus, a disease which disproportionally affects women and people of non-white ethnicities, groups often underrepresented in research. Treatment options are limited, can have life threatening side-effects and often don\u2019t slow the disease, which can then progress to end stage, requiring dialysis or a kidney transplant.
Professor Teresa Lambe OBE, Professor Julian Knight & Professor Jane McKeating have been elected as Fellows of the Academy of Medical Sciences, one of the most prestigious awards in the field.
The Centre for Medicines Discovery (CMD) and CAMS Oxford Institute (COI) at NDM, has recently partnered with Ono Pharmaceutical Co (Ono) to validate and develop novel targets in a bid to discover innovative medicines.
A Cell Reports study led by Prof. Benedikt Kessler provides an intricate time-resolved molecular map of different phases of NLRP3 inflammasome activation and unveils ubiquitin C-terminal hydrolase 1 (UCH-L1) as a modulator of NLRP3 inflammasome assembly and IL-1\u03b2 production.
The annual CAMS Oxford Institute Symposium was held on Monday 15th April 2024 in the Richard Doll Building on Old Road Campus for a full day of scientific talks, poster presentations & networking.
New research published in Nature Immunology showcases the collaborative efforts of CAMS Oxford Institute researchers to describe a novel pairing of integrins which could improve T cell control of cancer.
CAMS-Oxford Institute Principal Investigator, Ricardo Fernandes, has been awarded a competitive grant from Cancer Research UK to study anti-tumour T cell responses.
On 1st- 2nd of February 2024, Assistant Professor Yunlong Cao from Peking University, Beijing, China, visited the Chinese Academy of Medical Sciences Oxford Institute (COI), Nuffield Department of Medicine (NDM), University of Oxford.
In a study led by CAMS Researchers, patients were tracked for two years post COVID-19 infection in a bid to understand how memory immune responses decline over time and give insight into vaccination & booster strategies.
Researchers from the CAMS Oxford Institute and NDM Target Discovery Unit, including Prof. Benedikt Kessler and Dr. Ad\u00e1n Pinto-Fern\u00e1ndez, have collaborated with the team of Dr. Paul Geurink and Dr. Aysegul Sapmaz from Leiden University to investigate an important interferon-stimulated gene, ISG15.
A group of researchers led by Dr Roman Fischer at NDM\u2019s Target Discovery Institute, Centre for Medicines Discovery (CMD) and CAMS Oxford Institute Principal Investigator has developed a method to study proteins in human tumours by creating detailed maps that show how much of each protein is present in different parts of the tissue.
A Nature Communications study led by Professor Ling-Pei Ho\u2019s group provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.
An international team of scientists, including CAMS Oxford Institute group leaders Prof. Graham Ogg & Dr Yi-Ling Chen, have developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.
COI Postdoctoral scientist Dr Christina Heroven has been awarded a competitive Early Career Fellowship by the Wellcome Trust, providing funding for five years to support her career progression.
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