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During the past year, a plethora of structural information has provided detailed insights into the interactions between classical MHC class I molecules and their cognate receptors on T cells. Likewise, there have been major advances in our knowledge of the structures and functions of five nonclassical MHC-like molecules: HLA-DM (murine H2-M), HLA-E, HFE, ZAG and MIC-A.

Type

Journal article

Journal

Curr Opin Struct Biol

Publication Date

12/1999

Volume

9

Pages

745 - 753

Keywords

Animals, Humans, Immune System, Killer Cells, Natural, Major Histocompatibility Complex, Mice, Models, Molecular, Receptors, Antigen, T-Cell