Letter to the Editor: Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection.

Karp-Tatham E., O'Neill CR., Knight JC., Mentzer AJ., Chong AY.

Research into HLA-B*15:01 association with asymptomatic SARS-CoV-2 infection has so far yielded contradicting results. Using the UK Biobank cohort, we found a significant association between HLA-B*15:01 and asymptomatic infection. Our study adds more evidence for the complex role HLA alleles play in SARS-Cov-2 infection severity.

DOI

10.1016/j.xhgg.2024.100382

Type

Journal

HGG advances

Publication Date

11/2024

Addresses

The Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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