The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice
Tang W., Lu Y., Tian Q-Y., Zhang Y., Guo F-J., Liu G-Y., Syed NM., Lai Y., Lin EA., Kong L., Su J., Yin F., Ding A-H., Zanin-Zhorov A., Dustin ML., Tao J., Craft J., Yin Z., Feng JQ., Abramson SB., Yu X-P., Liu C-J.
A growth factor protects against arthritis in mice by blocking tumor necrosis factor–dependent signaling.