Using a specific antibody, we found that expression of the viral restriction factor IFITM3 differs across cell types within the immune compartment with higher expression in myeloid rather than lymphoid cells. IFITM3 expression was increased following IFN stimulation, mostly type I, in immune cells, with the exception of T cells.
European journal of immunology
03/2021
51
742 - 745
MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford University, Oxford, UK.
Lymphocytes, CD4-Positive T-Lymphocytes, Cell Line, Cell Line, Tumor, Humans, RNA-Binding Proteins, Interferon Type I, Membrane Proteins, Antiviral Agents, HEK293 Cells, A549 Cells