Chen Wu

Professor Wu's main research aims are to further analyzing genomic data of gastroenterology cancers and to characterize the functions and molecular mechanisms of identified genes and their variants in these cancers

She has been focusing on cancer genetics and genomics. Her group conducted several genome-wide association studies of esophageal squamous-cell carcinoma (ESCC), pancreatic cancer et al in Chinese populations and identified several novel loci or variants associated with risk of the development of these cancers. They have not only continued but also expanded the research into two aspects: one is to further analyze genomic data of esophageal and pancreatic cancer and the other is to characterize the functions and molecular mechanisms of identified genes and their variants in these cancers.

Current work is focusing on functional genomics screening of susceptible or driver genes and elucidation of the biological mechanisms of these genetic variations in ESCC.