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<jats:title>ABSTRACT</jats:title> <jats:p>Vaccine-induced cytotoxic T lymphocytes (CTL) have been implicated in the control of virus replication in simian immunodeficiency virus (SIV)-challenged and simian-human immunodeficiency virus-challenged macaques. Therefore, we wanted to test the impact that vaccine-induced CTL responses against an immunodominant Gag epitope might have in the absence of other immune responses. By themselves, these strong CTL responses failed to control SIVmac239 replication.</jats:p>

Original publication

DOI

10.1128/jvi.76.20.10507-10511.2002

Type

Journal article

Journal

Journal of Virology

Publisher

American Society for Microbiology

Publication Date

15/10/2002

Volume

76

Pages

10507 - 10511